Check out odds, insights and more in our betting preview for the Colorado Buffaloes vs. Arizona Wildcats college football matchup on October 16, 2021.

The Arizona Wildcats (0-5, 0-0 Pac-12) are 6.5-point underdogs in a road conference matchup against the Colorado Buffaloes (1-4, 0-0 Pac-12) on Saturday, October 16, 2021 at Folsom Field. The point total is set at 46.5.
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Odds for Colorado vs. Arizona
Odds courtesy of SI Sportsbook.
Over/Under Insights
- Colorado and its opponents have combined for 46.5 points — this matchup’s over/under — only twice this year.
- So far this season, 60% of Arizona’s games (3/5) have had more combined points than Saturday’s total of 46.5.
- Saturday’s over/under is 15.9 points higher than the combined 30.6 PPG average of the two teams.
- This contest’s over/under is 8.9 points fewer than the 55.4 these two squads combine to give up per game in 2021.
- The Buffaloes and their opponents have scored an average of 48.9 points per game in 2021, 2.4 more than Saturday’s total.
- In 2021, games involving the Wildcats have averaged a total of 54.6 points, 8.1 more than the set over/under in this contest.
Colorado Stats and Trends
- Colorado has one win against the spread in five games this year.
- Colorado’s games this year have gone over the point total one time in four opportunities (25%).
- This year, the Buffaloes put up 17.8 fewer points per game (13.8) than the Wildcats allow (31.6).
- The Buffaloes rack up 133.6 fewer yards per game (239.6), than the Wildcats allow per matchup (373.2).
- This year, the Buffaloes have turned the ball over five times, while the Wildcats have forced five.
- Find the latest spread and moneyline odds for Colorado at SISportsbook.
Arizona Stats and Trends
- So far this season Arizona has two wins against the spread.
- This year, the Wildcats have two against the spread wins in three games as an underdog of 6.5 points or more.
- Arizona’s games this season have gone over the point total two times in five opportunities (40%).
- The Wildcats rack up seven fewer points per game (16.8) than the Buffaloes give up (23.8).
- The Wildcats rack up 20.8 fewer yards per game (362.8) than the Buffaloes allow (383.6).
- When Arizona picks up over 383.6 yards, the team is 2-0 against the spread and 0-2 overall.
- This season the Wildcats have turned the ball over 12 times, nine more than the Buffaloes’ takeaways (3).
- Head to SISportsbook to find the latest moneyline, spread and over/under odds for this matchup.















