Check out odds, insights and more in our betting preview for the Ohio State Buckeyes vs. Indiana Hoosiers college football matchup on October 23, 2021.

Cfb Maryland Terrapins At Ohio State Buckeyes
The Indiana Hoosiers (2-4, 0-0 Big Ten) are 21-point underdogs in a home Big Ten matchup with the No. 5 Ohio State Buckeyes (5-1, 0-0 Big Ten) on Saturday, October 23, 2021 at Memorial Stadium. The over/under is set at 60.5.
For more great betting and fantasy insight, join the SI Winners Club Newsletter.
Odds for Ohio State vs. Indiana
Odds courtesy of SI Sportsbook.
Over/Under Insights
- Ohio State and its opponents have gone over the current 60.5-point total in all six games this season.
- Indiana’s games have gone over 60.5 points in three of six chances this season.
- The combined points per game average of the two teams, 70.8, is 10.3 points more than Saturday’s over/under.
- These two squads combine to surrender 47.3 points per game, 13.2 fewer than this contest’s over/under.
- The average total in Buckeyes games this season is 64.4, 3.9 points more than Saturday’s over/under of 60.5.
- In 2021, games involving the Hoosiers have averaged a total of 52.4 points, 8.1 fewer than this game’s set over/under.
Ohio State Stats and Trends
- Against the spread, Ohio State is 4-2-0 this season.
- The Buckeyes have been favored by 21 points or more three times this season and have covered the spread in two of them.
- Ohio State has gone over the point total in 66.7% of its opportunities this year (four times over six games with a set point total).
- This year, the Buckeyes score 21.7 more points per game (48.5) than the Hoosiers allow (26.8).
- Ohio State is 4-2 against the spread and 5-1 overall this season when the team scores more than 26.8 points.
- The Buckeyes average 562.7 yards per game, 229.5 more yards than the 333.2 the Hoosiers allow per contest.
- In games that Ohio State churns out over 333.2 yards, the team is 4-2 against the spread and 5-1 overall.
- The Buckeyes have turned the ball over five times this season, three fewer than the Hoosiers have forced (8).
- Find the latest spread and moneyline odds for Ohio State at SISportsbook.
Indiana Stats and Trends
- Thus far this year Indiana has one win against the spread.
- Indiana’s games this season have gone over the point total three times in six opportunities (50%).
- The Hoosiers score just 1.8 more points per game (22.3) than the Buckeyes surrender (20.5).
- Indiana is 1-2 against the spread and 2-1 overall when the team puts up more than 20.5 points.
- The Hoosiers rack up 47.5 fewer yards per game (340.0) than the Buckeyes give up (387.5).
- The Hoosiers have turned the ball over 12 times this season, one more turnover than the Buckeyes have forced (11).
- Head to SISportsbook to find the latest moneyline, spread and over/under odds for this matchup.















