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Clemson vs. Louisville College Football Odds, Plays and Insights

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Data Skrive
Nov 4, 2021 | 11:43 PM
Clemson vs. Louisville College Football Odds, Plays and Insights


Check out odds, insights and more in our betting preview for the Clemson Tigers vs. Louisville Cardinals college football matchup on November 6, 2021.

Oct 30, 2021; Clemson, South Carolina, USA; Clemson Tigers quarterback D.J. Uiagalelei (5) throws the ball against Florida State Seminoles defensive end Keir Thomas (4) during the fourth quarter at Memorial Stadium. Mandatory Credit: Ken Ruinard-USA TODAY Sports

The Clemson Tigers (5-3, 0-0 ACC) and the 21st-ranked run defense will visit the Louisville Cardinals (4-4, 0-0 ACC) and the 25th-ranked run offense on Saturday, November 6, 2021. The Cardinals are 4-point underdogs. The contest has a point total set at 46.5.

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Odds for Clemson vs. Louisville

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Over/Under Insights

  • Clemson and its opponents have gone over the current 46.5-point total in three of eight games this season.
  • Louisville’s games have gone over 46.5 points in four of seven chances this season.
  • The combined points per game average of the two teams, 50.7, is 4.2 points greater than Saturday’s over/under.
  • The 42.4 combined points per game that these two squads have allowed this season are 4.1 fewer than the 46.5 over/under in this contest.
  • The Tigers and their opponents have scored an average of 49.0 points per game in 2021, 2.5 more than Saturday’s total.
  • In 2021, games involving the Cardinals have averaged a total of 62.6 points, 16.1 more than the set total in this contest.

Clemson Stats and Trends

  • Clemson has one win against the spread in eight games this season.
  • This season, the Tigers have just one against the spread win in six games as a favorite of 4 points or more.
  • Clemson’s games this year have hit the over two times in eight opportunities (25%).
  • The Tigers put up 21.3 points per game, 5.8 fewer than the Cardinals allow per matchup (27.1).
  • Clemson is 1-1 against the spread and 2-0 overall in games when it puts up more than 27.1 points.
  • The Tigers collect 87.1 fewer yards per game (328.3) than the Cardinals allow per outing (415.4).
  • In games that Clemson churns out over 415.4 yards, the team is 0-2 against the spread and 2-0 overall.
  • The Tigers have 11 turnovers this season, equal to the number of takeaways for the Cardinals.
  • Find the latest spread and moneyline odds for Clemson at SISportsbook.

Louisville Stats and Trends

  • Against the spread, Louisville is 4-3-0 this year.
  • The Cardinals have been underdogs by 4 points or more three times this year and have covered the spread twice.
  • Louisville’s games this season have eclipsed the over/under two times in seven opportunities (28.6%).
  • The Cardinals rack up 29.4 points per game, 14.1 more than the Tigers surrender (15.3).
  • Louisville is 4-2 against the spread and 4-3 overall in games when it puts up more than 15.3 points.
  • The Cardinals collect 448.6 yards per game, 123.1 more yards than the 325.5 the Tigers give up.
  • Louisville is 4-3 against the spread and 4-4 overall when the team picks up over 325.5 yards.
  • The Cardinals have turned the ball over 12 times this season, one more turnover than the Tigers have forced (11).
  • Head to SISportsbook to find the latest moneyline, spread and over/under odds for this matchup.

Season Stats