Check out odds, plays and more for the Kansas City Chiefs vs. Buffalo Bills NFL Week 5 matchup on October 10, 2021.

The Buffalo Bills (3-1) will fight to keep their three-game winning streak intact as they are 3.5-point underdogs against the Kansas City Chiefs (2-2) on Sunday, October 10, 2021 at GEHA Field at Arrowhead Stadium.
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Odds for Chiefs vs. Bills
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Chiefs stats and trends
- Thus far this season Kansas City has one win against the spread.
- The Chiefs have been favored by 3.5 points or more four times this season and covered the spread in one of them.
- Kansas City’s games this year have hit the over three times in four opportunities (75%).
- This year, the Chiefs put up 22.5 more points per game (33.5) than the Bills surrender (11).
- Kansas City is 1-3 against the spread and 2-2 overall in games when it records more than 11 points.
- The Chiefs rack up 427.5 yards per game, 210.7 more yards than the 216.8 the Bills allow per contest.
- When Kansas City picks up more than 216.8 yards, the team is 1-3 against the spread and 2-2 overall.
- The Chiefs have turned the ball over seven times this season, four fewer than the Bills have forced (11).
- Click over to SISportsbook and find the latest spread, moneyline and total for Kansas City’s matchup with the Bills.
Bills stats and trends
- Buffalo has played four games, with three wins against the spread.
- Buffalo’s games this year have hit the over one time in four opportunities (25%).
- This season the Bills put up the same number of points per game that the Chiefs give up (31.3).
- When Buffalo records more than 31.3 points, it is 3-0 against the spread and 3-0 overall.
- The Bills rack up 33.8 fewer yards per game (404) than the Chiefs give up per outing (437.8).
- In games that Buffalo piles up more than 437.8 yards, the team is 2-0 against the spread and 2-0 overall.
- This season the Bills have turned the ball over four times, while the Chiefs have forced 4 turnovers.
Home and road insights
- At home, as 3.5-point favorites or greater, the Chiefs are winless ATS (0-2).
- The Bills are unbeaten ATS (1-0) on the road as 3.5-point underdogs or more.
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