Check out odds, insights and more in our betting preview for the Pittsburgh Panthers vs. Duke Blue Devils college football matchup on November 6, 2021.

The Pittsburgh Panthers (6-2, 0-0 ACC) visit the Duke Blue Devils (3-5, 0-0 ACC) on Saturday, November 6, 2021 in matchup between ACC foes at Brooks Field at Wallace Wade Stadium. Duke is a 21-point underdog. The point total is set at 64 for the game.
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Odds for Pittsburgh vs. Duke
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Over/Under Insights
- Pittsburgh and its opponents have combined to score more than 64 points in five of eight games this season.
- Duke and its opponents have combined to score more than 64 points in one game this season.
- The combined points per game average of the two teams, 68.4, is 4.4 points more than Saturday’s over/under.
- The 55.2 combined points per game that these two squads have allowed this season are 8.8 fewer than the 64 over/under in this contest.
- Panthers games have an average total of 55.6 points this season, 8.4 fewer than Saturday’s over/under.
- The 62.3 PPG average total in Blue Devils games this season is 1.7 points fewer than this game’s over/under.
Pittsburgh Stats and Trends
- Against the spread, Pittsburgh is 6-2-0 this year.
- This season, the Panthers have won against the spread in each of their two games as a favorite of 21 points or more.
- Pittsburgh’s games this year have hit the over in 75% of its opportunities (six times in eight games with a set point total).
- The Panthers rack up 43.9 points per game, 10.6 more than the Blue Devils surrender per outing (33.3).
- Pittsburgh is 4-2 against the spread and 4-2 overall this season when the team records more than 33.3 points.
- The Panthers average 529.1 yards per game, 56.6 more yards than the 472.5 the Blue Devils allow per matchup.
- In games that Pittsburgh amasses more than 472.5 yards, the team is 3-2 against the spread and 3-2 overall.
- The Panthers have eight giveaways this season, while the Blue Devils have 11 takeaways .
- Find the latest spread and moneyline odds for Pittsburgh at SISportsbook.
Duke Stats and Trends
- Duke is 4-4-0 against the spread this year.
- Duke’s games this season have eclipsed the over/under in 37.5% of its opportunities (three times in eight games with a set point total).
- The Blue Devils rack up just 2.6 more points per game (24.5) than the Panthers allow (21.9).
- When Duke puts up more than 21.9 points, it is 4-1 against the spread and 3-2 overall.
- The Blue Devils collect 452.6 yards per game, 112.5 more yards than the 340.1 the Panthers give up.
- In games that Duke picks up more than 340.1 yards, the team is 4-1 against the spread and 3-2 overall.
- The Blue Devils have turned the ball over three more times (15 total) than the Panthers have forced a turnover (12) this season.
- Head to SISportsbook to find the latest moneyline, spread and over/under odds for this matchup.
















