Check out odds, plays and more for the San Francisco 49ers vs. Minnesota Vikings NFL Week 12 matchup on November 28, 2021.

The San Francisco 49ers (5-5) and Minnesota Vikings (5-5) will face each other in Week 12 of the NFL season.
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Odds for 49ers vs. Vikings
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Over/under insights
- San Francisco and its opponents have gone over the current 49.5-point total in three of 10 games this season.
- So far this season, 50% of Minnesota’s games (5/10) have had more combined points than Sunday’s over/under of 49.5.
- The two teams combine to score 50.1 points per game, 0.6 more than the over/under in this contest.
- The 46.4 combined points per game that these two squads have allowed this season are 3.1 fewer than the 49.5 over/under in this contest.
- The average total in 49ers games this season is 47.1, 2.4 points fewer than Sunday’s total of 49.5.
- In 2020, games involving the Vikings have averaged a total of 50.0 points, 0.5 more than the set total in this contest.
49ers stats and trends
- San Francisco is 4-6-0 against the spread this season.
- This season, the 49ers have just two against the spread wins in six games as a favorite of 3.5 points or more.
- San Francisco’s games this year have gone over the total in five out of 10 opportunities (50%).
- The 49ers average just 0.4 more points per game (24.6) than the Vikings surrender (24.2).
- When San Francisco puts up more than 24.2 points, it is 3-2 against the spread and 4-1 overall.
- The 49ers rack up 359.3 yards per game, only 19.6 fewer than the 378.9 the Vikings allow per matchup.
- San Francisco is 1-2 against the spread and 2-1 overall when the team churns out more than 378.9 yards.
- The 49ers have turned the ball over 14 times this season, two more turnovers than the Vikings have forced (12).
- Click over to SISportsbook and find the latest spread, moneyline and total for San Francisco’s matchup with the Vikings.
Vikings stats and trends
- Minnesota has six wins against the spread in 10 games this year.
- The Vikings have been underdogs by 3.5 points or more three times this year and are 3-0 ATS in those contests.
- Minnesota has hit the over in 50% of its opportunities this season (five times in 10 games with a set point total).
- This season the Vikings score 3.3 more points per game (25.5) than the 49ers give up (22.2).
- Minnesota is 6-1 against the spread and 4-3 overall in games when it puts up more than 22.2 points.
- The Vikings rack up 68.7 more yards per game (387.0) than the 49ers give up per contest (318.3).
- Minnesota is 5-2 against the spread and 5-2 overall when the team churns out over 318.3 yards.
- The Vikings have turned the ball over six times, three fewer times than the 49ers have forced turnovers (9).
Home and road insights
- At home this year, San Francisco has one win against the spread and is 1-4 overall.
- At home, the 49ers are winless ATS (0-3) as 3.5-point favorites or more.
- San Francisco has hit the over in three of five home games this year.
- This season, 49ers home games average 48.3 points, 1.2 fewer than this outing’s over/under (49.5).
- On the road, Minnesota is 4-1 against the spread, and 2-3 overall.
- Minnesota has hit the over in four of five road games this season.
- This season, Vikings away games average 49.6 points, 0.1 more than this outing’s over/under (49.5).
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